The South Pearl is located 250 kilometres southeast of the capital of Cuba . To be more precise, it is situated on the northwest shore of the bay with the same name where there is also one of the most important ports in the Caribbean, not only due to the shipping of goods but also because of the recent starting up of an oil refinery.

It is the administrative centre of the province with the same name at latitude 21 degrees and 21 seconds and 23 degrees and 35 seconds north and at longitude 80 degrees and 20 seconds and 81 degrees and 10 seconds west.

It extends over 3.77% of the Cuban territory, that is, 4 177.2 sq km. It borders on the Caribbean Sea to the south, Villa Clara Province to the north, Sancti Spíritus to the east and Matanzas , the province where the beautiful Varadero beach is situated, to the west.